A compounded order

bamagirl26

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oh let me just vent a minute. So, before I found you awesome people, I used a bigco for Tz with b6 that got held in shipping in a weather delay and arrived to my house at 88 degrees. I requested a replacement since over 87 is like, not good, supposedly, but they said, Nooooo, its stable, its good, its fine, its safe. It was a good deal to me ($79 for a 40MG vial)... again, I was new to this!! but, id read that yeah, tirz is pretty stable ... I threw it in the fridge, but it still didnt sit right with me.. so I asked, hey, would u let me REORDER because it was a pretty sweet deal and my daughter also wanted to get back on it (and I figured Id give it to her (since I will be making my own experiments) So, I paid to reorder.. SPECIFICALLY requesting that they mail it out during the week, so it doesn't get trapped in transit and well, they created the label Thursday, and since then, its sat in warehouses in Florida(thurs), Tennessee(friday) and NJ since Saturday. It will arrive tomorrow. I KNOW it will have been in temps WAY beyond what is ok and the gel packs (they dont even use a cooler) will be warm.

I wrote today to say, no, you have two options here, resend me two replacements, because this is obviously now a systemic issue, not a one off, or refund my card. They said, No, its fine if it reaches 105 for a few days.. and I came back with the most science sounding letter, telling them that unless they can show me THIER PHARMACIES specific test data on the safety of their COMPOUNDED TZ with B6, I will not accept a blanket statement. So, we are talking $180.00.. I told them I will be writing to the FDA MedWatch, and FL and NJ pharmacy boards regarding violations of USP 1079- good storage and shipping practices, I also asked for a study that shows the alteration of thermodynamics via coformulation with pyridoxine (B6) , asserting that introduction of B6 into a sterile peptide solution inherently alters the formulations total ionic strength, ph Balance and molecular environment. I told them stability data from pure terzepitide can't be used as a blanket statement re temperature controls and told them that Pyridoxine at temperatures >88 degrees acts as a thermodynamic catalyst and accelerates degradation pathways. All of this from researching myself and a little help from AI, but I really hope they will reissue or refund. I HATE feeling ripped off.

I said that if the pharmacy doesnt possess lot specific empirical data validating their claims, the safety of the medication cannot be guaranteed and I asked them to provide their research, stability reports, and catch COA for my clinical review.

Hahahahah, did I go overboard?? But seriously, should I just fight this with my CC company, or do you reckon they will cave and just resend the meds... and before you ask why do I care, I have a lifetime supply... 1) principle and 2) I wanted to share with my daughter who also has an Rx.
 
It seems to depend on the telehealth/pharmacy. They can have very different “personalities” when it comes to customer service. WTG on standing up for yourself, learning (and teaching!) something in the process! It’s probably simpler to go through your CC re: a chargeback. On Reddit, people with disappointing experiences seemed to have better luck with their CC vs. the telehealths/pharmacies.

I know you don’t need this advice anymore, but I would always use a privacy card (single use or merchant specific virtual card) for telehealths. Shoot, months later I am still getting texts from telehealth “A” saying to complete paperwork for a refill. AS IF! Y’all mofos did not impress me, I spent way too much time with customer service already just trying to sign into the dang portal which never worked and I’ve already tried to cancel with you! So have fun charging that ghost card!

‘Sides, I’m hanging with the cool science kids now.
 
bamagirl26 said:


oh let me just vent a minute. So, before I found you awesome people, I used a bigco for Tz with b6 that got held in shipping in a weather delay and arrived to my house at 88 degrees. I requested a replacement since over 87 is like, not good, supposedly, but they said, Nooooo, its stable, its good, its fine, its safe. It was a good deal to me ($79 for a 40MG vial)... again, I was new to this!! but, id read that yeah, tirz is pretty stable ... I threw it in the fridge, but it still didnt sit right with me.. so I asked, hey, would u let me REORDER because it was a pretty sweet deal and my daughter also wanted to get back on it (and I figured Id give it to her (since I will be making my own experiments) So, I paid to reorder.. SPECIFICALLY requesting that they mail it out during the week, so it doesn't get trapped in transit and well, they created the label Thursday, and since then, its sat in warehouses in Florida(thurs), Tennessee(friday) and NJ since Saturday. It will arrive tomorrow. I KNOW it will have been in temps WAY beyond what is ok and the gel packs (they dont even use a cooler) will be warm.

I wrote today to say, no, you have two options here, resend me two replacements, because this is obviously now a systemic issue, not a one off, or refund my card. They said, No, its fine if it reaches 105 for a few days.. and I came back with the most science sounding letter, telling them that unless they can show me THIER PHARMACIES specific test data on the safety of their COMPOUNDED TZ with B6, I will not accept a blanket statement. So, we are talking $180.00.. I told them I will be writing to the FDA MedWatch, and FL and NJ pharmacy boards regarding violations of USP 1079- good storage and shipping practices, I also asked for a study that shows the alteration of thermodynamics via coformulation with pyridoxine (B6) , asserting that introduction of B6 into a sterile peptide solution inherently alters the formulations total ionic strength, ph Balance and molecular environment. I told them stability data from pure terzepitide can't be used as a blanket statement re temperature controls and told them that Pyridoxine at temperatures >88 degrees acts as a thermodynamic catalyst and accelerates degradation pathways. All of this from researching myself and a little help from AI, but I really hope they will reissue or refund. I HATE feeling ripped off.

I said that if the pharmacy doesnt possess lot specific empirical data validating their claims, the safety of the medication cannot be guaranteed and I asked them to provide their research, stability reports, and catch COA for my clinical review.

Hahahahah, did I go overboard?? But seriously, should I just fight this with my CC company, or do you reckon they will cave and just resend the meds... and before you ask why do I care, I have a lifetime supply... 1) principle and 2) I wanted to share with my daughter who also has an Rx.W

Click to expand...
Welcome mate!

You don't know till you know.... It's actually baffling when you start to dig and see prices.... and then you do the math realizing how much you spent.. and then you're sad... 🫣🫣😭😭

Also: way to go on standing up and giving them the business back. You won't really need them at one point when you find a couple of legit sources. 💪💪

Have a good one!

(Principal is what runs me in life sometimes.. 😆😆)
 
bamagirl26 said:


It was a good deal to me ($79 for a 40MG vial)...

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At first read I was thinking $79 is a KILLER deal...... then realized I was thinking in kits, not singles. Sigh. We are so spoiled in here.
 
HouseCat said:


It seems to depend on the telehealth/pharmacy. They can have very different “personalities” when it comes to customer service. WTG on standing up for yourself, learning (and teaching!) something in the process! It’s probably simpler to go through your CC re: a chargeback. On Reddit, people with disappointing experiences seemed to have better luck with their CC vs. the telehealths/pharmacies.

I know you don’t need this advice anymore, but I would always use a privacy card (single use or merchant specific virtual card) for telehealths. Shoot, months later I am still getting texts from telehealth “A” saying to complete paperwork for a refill. AS IF! Y’all mofos did not impress me, I spent way too much time with customer service already just trying to sign into the dang portal which never worked and I’ve already tried to cancel with you! So have fun charging that ghost card!

‘Sides, I’m hanging with the cool science kids now.

Click to expand...
fortunately, I did just that, so they cant torment me in the future. I will probs just take it up with the CC company if they dont come back in 48 hours with a resolution. One passes the buck to the other, and what I dont get is they can fully claim it w UPS who BOTH times didnt fulfill their timeline obligations. I dont get why they are being so difficult. Also, the med has a very quickly approaching BUD, so like, they will be tossing the meds anyway!. send me my shiiiiiii
 
I think you should refrain from ordering in the summer if you’re concerned about the temperature. Reshipping is not going to address your concern if it’s still hot outside. The peps are most likely find. They sit in warehouses, hot cargo areas on planes, the back of shipping trucks, etc but they are find to use as long as they are not in liquid form. Refusing to pay and reporting the company is crazy work.
 
tbaby said:


I think you should refrain from ordering in the summer if you’re concerned about the temperature. Reshipping is not going to address your concern if it’s still hot outside. The peps are most likely find. They sit in warehouses, hot cargo areas on planes, the back of shipping trucks, etc but they are find to use as long as they are not in liquid form. Refusing to pay and reporting the company is crazy work.

Click to expand...
They are in liquid form, she's discussing compounded tirz. That said, it is probably fine, but other compounding pharmas are addressing this with more awesome shipping containers-adorable vacuum sealed tumblers with ice packs...but I don't need them.
 
endlrls said:


Welcome mate!

You don't know till you know.... It's actually baffling when you start to dig and see prices.... and then you do the math realizing how much you spent.. and then you're sad... 🫣🫣😭😭

Also: way to go on standing up and giving them the business back. You won't really need them at one point when you find a couple of legit sources. 💪💪

Have a good one!

(Principal is what runs me in life sometimes.. 😆😆)

Click to expand...
yeah, I have PLENTY to last, but if there is one thing that really irks me is lack of integrity - and then madness at myself for giving people a change to get it right when deep down I should just trust that they wont!

tbaby said:


I think you should refrain from ordering in the summer if you’re concerned about the temperature. Reshipping is not going to address your concern if it’s still hot outside. The peps are most likely find. They sit in warehouses, hot cargo areas on planes, the back of shipping trucks, etc but they are find to use as long as they are not in liquid form. Refusing to pay and reporting the company is crazy work.

Click to expand...
no, thats now what happened. I did pay, 2 x's for two orders, but one shipment arrived at 89 degrees. I wont be ordering more, I have a new supply. but it's terrible business to not stand behind a shipment issue. The guidelines online all say over 87 is a NO GO, discard and contact pharmacy. I did, and the response has been atrocious. I asked them to provide the temp study, I dont think that is unreasonable, resend the product using better therm controls/shipping method..not a brown UPS box that isnt in a cooler, or refund since I was sent something un-usable. If you think that's crazy work, I guess we have different tolerances for being ripped off. I am actually pretty easy going.
 
bamagirl26 said:


yeah, I have PLENTY to last, but if there is one thing that really irks me is lack of integrity - and then madness at myself for giving people a change to get it right when deep down I should just trust that they wont!

no, thats now what happened. I did pay, 2 x's for two orders, but one shipment arrived at 89 degrees. I wont be ordering more, I have a new supply. but it's terrible business to not stand behind a shipment issue. The guidelines online all say over 87 is a NO GO, discard and contact pharmacy. I did, and the response has been atrocious. I asked them to provide the temp study, I dont think that is unreasonable, resend the product using better therm controls/shipping method..not a brown UPS box that isnt in a cooler, or refund since I was sent something un-usable. If you think that's crazy work, I guess we have different tolerances for being ripped off. I am actually pretty easy going.

Click to expand...
But if you really don't want it, I'll use it 😂😂😂😂
 
So you ordered the discount tirz with the BUD on 8/2/26 but upset it was 88 degrees f out? It's fine up to 105 degrees f. I am also confused why you ordered the 40mg vials which was priced higher per mg than the 68mg vials which also had a BUD of October. Anyway, the 40s arent available anymore.
 
bamagirl26 said:


It was a good deal to me ($79 for a 40MG vial)... again, I was new to this!!

Click to expand...
Sigh, I paid $220 a month for 4 prefilled 2.5 mg Tirzepatide / B12 syringes for my first two months. How many kits would that have been? I refuse to do the math and make myself cry.
 
viglnt26 said:


Sigh, I paid $220 a month for 4 prefilled 2.5 mg Tirzepatide / B12 syringes for my first two months. How many kits would that have been? I refuse to do the math and make myself cry.

Click to expand...
Well, My FIRST 10MG vial was 200 if you wanna feel better. TEN Milligrams! LOL. Next 30 MG was 260, so even tho they were "good deals", I was upset with the poor customer service. I dont expect amazing CS from gray, but surprisingly, my interactions have been wonderful! I told hubby, I feel better to be in this space because I can manage expectations, expect a few blips along the way, and know im still making out SO far ahead!
 
viglnt26 said:


Sigh, I paid $220 a month for 4 prefilled 2.5 mg Tirzepatide / B12 syringes for my first two months. How many kits would that have been? I refuse to do the math and make myself cry.

Click to expand...
Oh, I just re-read your post, so yeah, you were on the same expensive train!!
 
bamagirl26 said:


Oh, I just re-read your post, so yeah, you were on the same expensive train!!

Click to expand...
At least mine was a 20 minute drive to a small compounding pharmacy. Loved the pharmacy, they were great.....but not $220 great when I pay what I pay now.
 
viglnt26 said:


At least mine was a 20 minute drive to a small compounding pharmacy. Loved the pharmacy, they were great.....but not $220 great when I pay what I pay now.

Click to expand...
YEAH, for real! Pre filled vials and all. These meds-spas must be making Bank! Good for them honestly. Glad you (and I) have found better options 🙂
 
bamagirl26 said:


yeah, I have PLENTY to last, but if there is one thing that really irks me is lack of integrity - and then madness at myself for giving people a change to get it right when deep down I should just trust that they wont!

no, thats now what happened. I did pay, 2 x's for two orders, but one shipment arrived at 89 degrees. I wont be ordering more, I have a new supply. but it's terrible business to not stand behind a shipment issue. The guidelines online all say over 87 is a NO GO, discard and contact pharmacy. I did, and the response has been atrocious. I asked them to provide the temp study, I dont think that is unreasonable, resend the product using better therm controls/shipping method..not a brown UPS box that isnt in a cooler, or refund since I was sent something un-usable. If you think that's crazy work, I guess we have different tolerances for being ripped off. I am actually pretty easy going.

Click to expand...
Yes.... Integrity can be a Goocher.... I get emails now from the US resellers and I just say out loud "you F*cking snake in the grass..." and then I cry about the amount of money I overspent 😭😭
 
Have you ever noticed that most US postal service vehicles do not have air conditioning? If it comes in the mail... ponder that thought.

Any and all meds you order will experience this. Even with rush shipping, there is no guarantee that the product did not sit in the hot (or cold) belly of a plane or truck during shipment.

Tirz is not that unstable and I will gladly use any and all that you are not comfortable with.

If you want something that is literally that unstable, look the unstablized version of R-ALA, which is a supplement. Don't confuse R-ALA with the stabilized version which is Na-R-ALA or with plain ALA, both of those versions are heat stable.

Once again, I am not worried about the shipping. For all we know, the delayed shipment could have been in a climate controlled warehouse duing that delay. Or not. It really does not matter.

If you want to get worried about something, you realize that over supplementation of B6-HCl (pyridoxine hydrochloride) can result in nerve toxicity (peripheral neuropathy) Note that this is the -HCl form. The other forms of B6 are still safe.

Australia (New Regulations of B6-HCl): Doses above 50 mg up to 200 mg require pharmacist supervision (Schedule 3), and doses of 200 mg or higher require a prescription (Schedule 4). Doses over 10 mg require peripheral neuropathy warnings.

So anyone and everyone can now start researching ALA supplement stability and B6-HCl cumulative toxicity and new regulations. You can follow up with the active B6 form, Pyridoxal 5'-phosphate (P5P), which is not linked to neuropathy. This disparity is driven by a unique biological mechanism known as the "B6 Paradox."

So take a deep breath and relax. It was very irritating but everything is ok. 🙂
 
moodymama76 said:


So you ordered the discount tirz with the BUD on 8/2/26 but upset it was 88 degrees f out? It's fine up to 105 degrees f. I am also confused why you ordered the 40mg vials which was priced higher per mg than the 68mg vials which also had a BUD of October. Anyway, the 40s arent available anymore.

Click to expand...
it was the only one they would let me order bc I am on low dose, I wasnt upset it was 88 degrees F outside. The medicine temperature arrived at 88.5 degrees when I unpacked it IN the house, and though it may be "safe" to use, I've read enough in the past two weeks to learn about Peptide degradation.

Just A Cat said:


Have you ever noticed that most US postal service vehicles do not have air conditioning? If it comes in the mail... ponder that thought.

Any and all meds you order will experience this. Even with rush shipping, there is no guarantee that the product did not sit in the hot (or cold) belly of a plane or truck during shipment.

Tirz is not that unstable and I will gladly use any and all that you are not comfortable with.

If you want something that is literally that unstable, look the unstablized version of R-ALA, which is a supplement. Don't confuse R-ALA with the stabilized version which is Na-R-ALA or with plain ALA, both of those versions are heat stable.

Once again, I am not worried about the shipping. For all we know, the delayed shipment could have been in a climate controlled warehouse duing that delay. Or not. It really does not matter.

If you want to get worried about something, you realize that over supplementation of B6-HCl (pyridoxine hydrochloride) can result in nerve toxicity (peripheral neuropathy) Note that this is the -HCl form. The other forms of B6 are still safe.

Australia (New Regulations of B6-HCl): Doses above 50 mg up to 200 mg require pharmacist supervision (Schedule 3), and doses of 200 mg or higher require a prescription (Schedule 4). Doses over 10 mg require peripheral neuropathy warnings.

So anyone and everyone can now start researching ALA supplement stability and B6-HCl cumulative toxicity and new regulations. You can follow up with the active B6 form, Pyridoxal 5'-phosphate (P5P), which is not linked to neuropathy. This disparity is driven by a unique biological mechanism known as the "B6 Paradox."

So take a deep breath and relax. It was very irritating but everything is ok. 🙂

Click to expand...
yeah, already over it. Was just a frustrating vent, for which Ive learned, they last for days when posted online, so kinda silly to vent online. Interesting info on the B6 tho. I used to take tablet form as a diuretic when I felt bloated and some days id feel tingly fingers. I will have to read up on that! Thanks for your info
 
bamagirl26 said:


it was the only one they would let me order bc I am on low dose, I wasnt upset it was 88 degrees F outside. The medicine temperature arrived at 88.5 degrees when I unpacked it IN the house, and though it may be "safe" to use, I've read enough in the past two weeks to learn about Peptide degradation.

Click to expand...
Well your here now so you'll be good and didn't really need the info I'm about to say. But early on when I went to compounds I found the telehealth that didn't require proof of rx. I know of 3 of them. I told them I was on 15mg. I was only on 5mg. I took that rx to the preferred telehealths that did require an rx and have them that. I've been supplying myself and 2 adult children with tirz since Jan, we split the costs.
 
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