1st shot 5/25

birdwhacker said:

GLPFrodo said:

birdwhacker said:

GLPFrodo said:

birdwhacker said:

BNLFL said:

kmngq said:

Took my 2nd injection on Sunday. 1mg.

Honestly, I have no idea whether it's doing anything. I suppose not having any side effects is a positive thing.
That dose is on the low side. Either follow what @birdwhacker suggested, or keep it there for a full 4 weeks so it accumulates in your body, then raise it to 2mg.

birdwhacker said:

BNLFL said:

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.
Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

  • https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  • https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  • https://a.co/d/08mqDPmk 2 every morning before eating.
That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male
It's not that I doubt you — this is simply how I do things. One injection weekly for us. As I see it, the hunger blunting stays steady. Over 19 weeks: 46lbs, which works out to 2.4lb each week on average.
BNLFL, that wasn't aimed at you! I was referring to folks who don't have your level of coolness. You're among the good ones!
Mind passing that message along to my wife, brother? 🤣 🤣
Honestly, the only situations where I'd say 1mg makes sense are if someone is extremely sensitive, or if their diet and appetite are already dialed in.

In my own family, I saw 2 people begin at 1mg and then move to 2mg 4 weeks later. To me that looks like a clever method for burning time and ruining how well the drug will work down the road.

My mom was 1 of them. She ended up needing 6mg per week instead of 4mg, since 5mg wasn't sufficient for her. My take is that 1mg makes you tolerant to the drug quite fast. Acclimating takes only 1-2 weeks, and most side effects clear up within 3-4 weeks.
From some study material I went through, beginning at a lower dose seems to aid adaptation — or plasticity, to use their term — and greatly lessens side effects while a person titrates upward. When the starting dose was higher, the findings indicated the body never adjusted, and those in that group continued to have noticeably more side effects.
That's just some anonymous individual's claim, not research. Going in too high or ramping up too fast is clearly a bad idea, but the goal should be to begin at or close to a dose that actually works. Begin too low and your responsiveness to the medication fades, meaning you'll need more of it to get results other people reach on a smaller amount.
Or maybe at 28 you don't have all the answers, and it was a study...
Do you have a source for what you copied and pasted? It reads like AI.

Those studies began at 2mg and 4mg.
Let me pull up something I saw posted not long ago and replied to:

"Nope, I'm not going to cite my source, since I'm not a nerd. Just search it yourself."

😂
 
GLPFrodo said:

birdwhacker said:

GLPFrodo said:

birdwhacker said:

GLPFrodo said:

birdwhacker said:

BNLFL said:

kmngq said:

Took my 2nd injection on Sunday. 1mg.

Honestly, I have no idea whether it's doing anything. I suppose not having any side effects is a positive thing.
That dose is on the low side. Either follow what @birdwhacker suggested, or keep it there for a full 4 weeks so it accumulates in your body, then raise it to 2mg.

birdwhacker said:

BNLFL said:

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.
Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

  • https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  • https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  • https://a.co/d/08mqDPmk 2 every morning before eating.
That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male
It's not that I doubt you — this is simply how I do things. One injection weekly for us. As I see it, the hunger blunting stays steady. Over 19 weeks: 46lbs, which works out to 2.4lb each week on average.
BNLFL, that wasn't aimed at you! I was referring to folks who don't have your level of coolness. You're among the good ones!
Mind passing that message along to my wife, brother? 🤣 🤣
Honestly, the only situations where I'd say 1mg makes sense are if someone is extremely sensitive, or if their diet and appetite are already dialed in.

In my own family, I saw 2 people begin at 1mg and then move to 2mg 4 weeks later. To me that looks like a clever method for burning time and ruining how well the drug will work down the road.

My mom was 1 of them. She ended up needing 6mg per week instead of 4mg, since 5mg wasn't sufficient for her. My take is that 1mg makes you tolerant to the drug quite fast. Acclimating takes only 1-2 weeks, and most side effects clear up within 3-4 weeks.
From some study material I went through, beginning at a lower dose seems to aid adaptation — or plasticity, to use their term — and greatly lessens side effects while a person titrates upward. When the starting dose was higher, the findings indicated the body never adjusted, and those in that group continued to have noticeably more side effects.
That's just some anonymous individual's claim, not research. Going in too high or ramping up too fast is clearly a bad idea, but the goal should be to begin at or close to a dose that actually works. Begin too low and your responsiveness to the medication fades, meaning you'll need more of it to get results other people reach on a smaller amount.
Or maybe at 28 you don't have all the answers, and it was a study...
Do you have a source for what you copied and pasted? It reads like AI.

Those studies began at 2mg and 4mg.
Let me pull up something I saw posted not long ago and replied to:

"Nope, I'm not going to cite my source, since I'm not a nerd. Just search it yourself."

😂
Alright. Since the text in that image of yours comes from AI, I have to figure the data does too – or at minimum, it could be distorted. They're your monkies, so it's not my place to tell you what to do with them!

Edit: I checked, and the research you're citing isn't real. What you might have come across is data that's been misread about GI tolerability at lower doses. To be exact, that wording about "plasticity" and "adaptation" hasn't been used.
 
Powerslide said:

Sitting at roughly 210 now.

Switched to 2mg on 6/29, and I've kept to that schedule every 6 days since.

I'm still drawing from the original vial, which makes it about 80 days old by now. From what I gather, the majority of folks aim to finish theirs inside 60 days. The only size I could get was a 30mg, so that's the one I reconstituted. Lately it feels like the headache side effects are ramping up rather than easing off during the first couple days following the pin. I'm trying to figure out whether this is a hydration thing or possibly tied to how long the vial has been sitting.

If anyone has run reta beyond the 60 day mark after reconstituting, I'd like to hear whether their sides got worse as the vial got older.
Since I began Reta, headaches have never been an issue for me. In fact, from 2mg all the way up to 10mg, I haven't experienced any notable side effects.

When it comes to my reconstituted Reta, I'm a 8 week, 60 days guy, though I'll stretch it to 10 weeks if necessary.
 
Keeping it at 2mg weekly and the scale keeps moving down. Since the pounds are still dropping, I don't feel any pull to increase the dose. A gentler decline seems kinder to both skin and muscle, I'd imagine.

5/25 start: 238

8/19: 205

8/30: 201
 
I appreciate how thorough your log is — following someone as they move through the early stages is genuinely fascinating. Since I’m just starting out myself, the initial step and those opening weeks are exactly what I want to understand best.
 
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