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Given your situation, my suggestion would be to begin at 1 mg of Reta while lowering the Tirz. to match.

Whatever you decide to use is up to you—no physician needs to give permission. I simply inform my doctors that I'm on it. That's all there is to it. And conversely, I don't blindly accept every recommendation or prescription a doctor gives me either!

Tirz had me stuck and I was actually putting weight back on. Combining Tirz with Reta ended up being effective in my case.

Overview of 3 weeks: Combining MJ (13 mg) with Reta (2 mg) produced a drop of -5,1 KG -11,24 lbs. Over the 5 weeks since MJ was raised to 15 mg and then stacked with Reta, the reduction has been: -6,7 KG -14,77 lbs.

Sure, why not? Last week I also went to a cardiologist for a check-up. She asked what medications I take. I told her about my Tirzepatide and Retatrutide stack. My bigger worry was that she wouldn't recognize either name! I'm going to find a different doctor — that was my first visit there...

Lowering the MJ dose is something I'll attempt, yeah. Today marked my first 2 mg Reta shot. My last MJ injection was 15 mg, 2 days back. Next time I might reduce it. It all comes down to how I feel overall.

On MJ my pulse went up roughly 5-10 bpm. Before any GLPs my RHR sat at 55 bpm, and these days it reads 60-65 bpm. It hasn't dropped back since. My mother had the same pattern: once she quit, her RHR returned to where it started. I'm sure the identical thing would happen to me if I ever stop MJ...

Thanks for laying out your experience in such detail! And well done on everything you've achieved 😎 As I mentioned, dropping a few more KG is still my goal, so a higher dose will likely be necessary for that to happen. That's especially true given how long I've been on MJ at this point. On top...

Thanks. No, it wasn't advised. I talked it over, but I'll be upfront with my Dr. and let him know after I've begun it.

So my approach is to combine them. As I mentioned, right now I'm on 15 mg of Mounjaro. Once I begin Reta, my plan is 2 mg Reta plus 13 mg MJ, then adjust from there. I've come across several accounts saying Reta doesn't suppress appetite as strongly as MJ, but by stacking them I might cover that...

At 15 mg of MJ, suppression has completely stopped for me, which is why I'm making the change. Reta hasn't been started yet — that begins next week. Should Reta prove completely ineffective (my plan is to stay on it for a minimum of 3 month), I'll do a "reset": quit every medication for a few...

Hey all! I've just joined this GLP1Chat after reading quietly for some time, and I figured it was finally time to tell my story. Maybe it'll motivate somebody, or at least get a good conversation going. My journey began close to 2 years back, when I weighed roughly 175kg and felt utterly lost...