CHK- CU / COPD benefits

Schwossy

Schwossy

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About 20 years back, I received a COPD diagnosis; the condition cannot be cured, and the only thing possible is holding things where they are. Recently, after reading many scientific papers and following this forum, I came across information on what GHK-Cu might do. According to what I read, it can cause a gene reset and, via its active components, act favorably and directly on lung tissue that has been damaged.



Glycyl‐l‐histidyl‐l‐lysine‐Cu2+ rescues cigarette smoking‐induced skeletal muscle dysfunction via a sirtuin 1‐dependent pathway - PMC

Skeletal muscle dysfunction is an important co‐morbidity in patients with chronic obstructive pulmonary disease (COPD) and is significantly associated with increased mortality. Oxidative stress has been demonstrated an important trigger for ...
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
 
On this forum I've come across plenty of accounts of GHK-Cu, and the one side effect that keeps coming up is a burning feeling where you inject.

So I've volunteered myself as a guinea pig. A GHK-Cu kit is on order, and tomorrow is when it should show up.

My plan is a daily 1.5 mg dose for a year. Once that year has passed, I'll book an appointment with a pulmonologist to find out whether anything has improved in a meaningful way. That said, I'm also hoping some positive changes will show up while the experiment is running. If all I end up with is nicer skin and fingernails, fine—but as I see it, the possible upside outweighs the risk.
 
Schwossy said:

On this forum I've come across plenty of accounts of GHK-Cu, and the one side effect that keeps coming up is a burning feeling where you inject.

So I've volunteered myself as a guinea pig. A GHK-Cu kit is on order, and tomorrow is when it should show up.

My plan is a daily 1.5 mg dose for a year. Once that year has passed, I'll book an appointment with a pulmonologist to find out whether anything has improved in a meaningful way. That said, I'm also hoping some positive changes will show up while the experiment is running. If all I end up with is nicer skin and fingernails, fine—but as I see it, the possible upside outweighs the risk.
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the burning can get genuinely severe — bad enough that people stop using it. What drives that burn is leftover copper in the solution, and there are two ways to reduce it: a) introduce plain GHK (the basic form, without copper) so the extra copper gets bound up, or b) run the solution through a 0.22 micron PES filter, which traps the surplus copper (as long as sterility is maintained throughout). Best of luck with it — I've been on GHK for close to 2 straight years at this point.
 
Schwossy said:

On this forum I've come across plenty of accounts of GHK-Cu, and the one side effect that keeps coming up is a burning feeling where you inject.

So I've volunteered myself as a guinea pig. A GHK-Cu kit is on order, and tomorrow is when it should show up.

My plan is a daily 1.5 mg dose for a year. Once that year has passed, I'll book an appointment with a pulmonologist to find out whether anything has improved in a meaningful way. That said, I'm also hoping some positive changes will show up while the experiment is running. If all I end up with is nicer skin and fingernails, fine—but as I see it, the possible upside outweighs the risk.
Click to expand...

trojanpeptide said:

the burning can get genuinely severe — bad enough that people stop using it. What drives that burn is leftover copper in the solution, and there are two ways to reduce it: a) introduce plain GHK (the basic form, without copper) so the extra copper gets bound up, or b) run the solution through a 0.22 micron PES filter, which traps the surplus copper (as long as sterility is maintained throughout). Best of luck with it — I've been on GHK for close to 2 straight years at this point.
Click to expand...
I have also come across the idea that Saline sterile water works better than bac water - it cuts down on or gets rid of the burning or pain that comes with ghk-cu .....I still need to pick some up so I can give it a try.

When it comes to Copd and Ghk-cu, I have not come across any reading on it.

My ghk-cu goes into the glutes or thighs, deep, using a 1/2" syringe pushed in far - that appears to help quite a bit.

Whether 1.5mg will do much in your case, I honestly can't say....my own amount is 6.5mg per day - my skin responds nicely to it - and I definitely see it in my feet.

As for Copd- VIP is said to be a big help when it comes to lowering respiratory inflammation - Foxdri-04 might be worth looking into as well, for sentient cell elimination- it is not a pleasant pep - even though it works very well- from what I've read it makes a massive difference for people dealing with arthritis (which is something I have) And lastly - gluthathione could be of help too- I have never given it a try. Both Foxdri-04 and Vip are things I plan to try - even though COPD isn't something I have.

Pep-pedia.org is a really good resource- though I imagine you're already aware of it.

Wishing you the best with your research - I hope everything works out for you
 
trojanpeptide said:

the burning can get genuinely severe — bad enough that people stop using it. What drives that burn is leftover copper in the solution, and there are two ways to reduce it: a) introduce plain GHK (the basic form, without copper) so the extra copper gets bound up, or b) run the solution through a 0.22 micron PES filter, which traps the surplus copper (as long as sterility is maintained throughout). Best of luck with it — I've been on GHK for close to 2 straight years at this point.
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@trojanpeptide How much are you taking each day? And what changes have you seen?
 
Riviera said:

I have also come across the idea that Saline sterile water works better than bac water - it cuts down on or gets rid of the burning or pain that comes with ghk-cu .....I still need to pick some up so I can give it a try.

When it comes to Copd and Ghk-cu, I have not come across any reading on it.

My ghk-cu goes into the glutes or thighs, deep, using a 1/2" syringe pushed in far - that appears to help quite a bit.

Whether 1.5mg will do much in your case, I honestly can't say....my own amount is 6.5mg per day - my skin responds nicely to it - and I definitely see it in my feet.

As for Copd- VIP is said to be a big help when it comes to lowering respiratory inflammation - Foxdri-04 might be worth looking into as well, for sentient cell elimination- it is not a pleasant pep - even though it works very well- from what I've read it makes a massive difference for people dealing with arthritis (which is something I have) And lastly - gluthathione could be of help too- I have never given it a try. Both Foxdri-04 and Vip are things I plan to try - even though COPD isn't something I have.

Pep-pedia.org is a really good resource- though I imagine you're already aware of it.

Wishing you the best with your research - I hope everything works out for you
Click to expand...
there's a study here.

Riviera said:

I have also come across the idea that Saline sterile water works better than bac water - it cuts down on or gets rid of the burning or pain that comes with ghk-cu .....I still need to pick some up so I can give it a try.

When it comes to Copd and Ghk-cu, I have not come across any reading on it.

My ghk-cu goes into the glutes or thighs, deep, using a 1/2" syringe pushed in far - that appears to help quite a bit.

Whether 1.5mg will do much in your case, I honestly can't say....my own amount is 6.5mg per day - my skin responds nicely to it - and I definitely see it in my feet.

As for Copd- VIP is said to be a big help when it comes to lowering respiratory inflammation - Foxdri-04 might be worth looking into as well, for sentient cell elimination- it is not a pleasant pep - even though it works very well- from what I've read it makes a massive difference for people dealing with arthritis (which is something I have) And lastly - gluthathione could be of help too- I have never given it a try. Both Foxdri-04 and Vip are things I plan to try - even though COPD isn't something I have.

Pep-pedia.org is a really good resource- though I imagine you're already aware of it.

Wishing you the best with your research - I hope everything works out for you
Click to expand...
i hit my love handles, into the fat, not that there's much left.

Riviera said:

@trojanpeptide How much are you taking each day? And what changes have you seen?
Click to expand...
I only use 2.5mg GHK-Cu, but that includes 0.5mg KPV and MT1 (in 10U total).

My schedule is 5/2. Using more isn't something I want to do; my aortic root is dilated and I'd rather not make it worse; healing is the goal here.

If the purpose were skin care, for instance my face, or scars, then microneedling with it would be my approach. Hairloss would get the same treatment. Down the road I intend to mix up a serum, I've just been sooo busy (I know, who isn't...)

As for the water... my own BAC gets made by me. Whether this was an issue I can't say, but you never know. Right now, using my own stash has me very satisfied 😉
 
It doesn't look like taking GHK-Cu in huge quantities automatically produces stronger effects. Based on what I've come across so far, 1–2 mg per day is regarded as the optimal amount. Somewhere I also saw mention of a short human tolerability trial run earlier this year, in which 2 mg was the highest dose injected. A lot of people suggest—much like the BPC-157 protocol—doing 8–12 weeks on and then taking 4 weeks off; that advice, though, was aimed at skin and hair, neither of which matters to me. My package has just shown up, and today I'll give myself the first dose.
 
For my protocol I run the wolverine stack of bpc157/tb500 together with GHK-Cu 3mg, plus a generous amount of additional bac water. There is a sting from the injections and the soreness sticks around afterward. My prednisone thinned skin heals up thanks to it. I had really bad purple skin lesions and it wiped that out almost 100%. The thin skin repairs more effectively and is less easily damaged. At 62, I resembled a corpse until the copper peptides
 
Yesterday I mixed the GHC CU 50 mg with 3.5 ml of bacteriostatic water, then filled an injector pen with 3 ml of that solution.

At the moment we're finishing off what's still in the vial (my girlfriend uses it as well, for cosmetic reasons). After drawing the dose, I wipe the needle once more with an alcohol swab. For the two of us it's only a short burning feeling that lasts a few seconds, and after that everything's fine—no swelling, redness, etc. The injection site is the subcutaneous fat on the thigh.

Things are going well so far.
 
I was going through some YouTube videos about N-Acetyl Cysteine. A lot of the doctors in those videos stated that NAC can be helpful for COPD. So I ran a search, and the first result that appeared was this older video. It could be worth giving a shot. It's relatively inexpensive and easy to find just about anywhere. Look into it for yourself 😉

View: https://www.youtube.com/watch?v=NukCKs_dPDk
 
I hope this works for you!

Cu has given me excellent cosmetic outcomes, particularly for my feet. For decades I had cracked heels that nothing could touch to improve. Since week 7 or 8 there has been no cracking. I don't cycle off. Every day I pin 4mg/day.
 
Hope this is useful! From what I've seen myself, my skin and hair both look and feel a lot healthier. As for the burn.. I don't actually get a burn, what I get is a sting straight from the depths of hell that hits in the middle of the night, at least once a week oof. Putting KPV in with it has made a pretty big difference.
 
I realize we're talking about GHK-Cu rather than GLP-1s, but the case for GLP-1 agonists cutting COPD severity or flare-ups is honestly pretty solid, still growing, and under active investigation. Everything so far comes from population-level data or comparisons of outcomes across different medications, not from the stronger randomised controlled prospective clinical trials — yet the findings to date are promising enough that funding those much pricier definitive trials would be justified. Also, the gains showed up beyond just obese COPD patients. I'll be honest: I haven't dug into GHK and COPD specifically, though I'd be shocked if the supporting evidence came anywhere close to what exists for GLP drugs. Most folks here are probably already taking GLP medications, but it seemed worth a mention.
 
lessthanhalf said:

I realize we're talking about GHK-Cu rather than GLP-1s, but the case for GLP-1 agonists cutting COPD severity or flare-ups is honestly pretty solid, still growing, and under active investigation. Everything so far comes from population-level data or comparisons of outcomes across different medications, not from the stronger randomised controlled prospective clinical trials — yet the findings to date are promising enough that funding those much pricier definitive trials would be justified. Also, the gains showed up beyond just obese COPD patients. I'll be honest: I haven't dug into GHK and COPD specifically, though I'd be shocked if the supporting evidence came anywhere close to what exists for GLP drugs. Most folks here are probably already taking GLP medications, but it seemed worth a mention.
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It seems like each time I visit this site, I come across yet another impressive benefit that GLP-1s offer us.
 
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