Is Kisspeptin-10 worth trying?

Bep2030

Bep2030

Explorer
Joined
Aug 3, 2026
Messages
22
Reaction score
0
Location
The Netherlands
Hey! Kisspeptin-10 is on my list to try, to see whether it helps my libido, which has dropped quite a bit since being on reta.

If anyone here has used Kisspeptin-10 (especially females) for a similar reason, I'd love to hear about it. How did it go? Any difference in libido, and if so, how quickly?

On dosing I'm curious too: what was the dose, and how often each week? Any side effects, or anything else worth knowing?
 
Not something I've tried, though I hope your thread draws some replies, since Kisspeptin doesn't come up very often around the forum.
 
Thank you @Calm Logic. Kisspeptin is something I've been reading up on…with my family history, I'm very protective of my heart 😂

My experimenting has been with PT-141, so far unsuccessfully….there is apparently a threshold to hit there, and hit it I have not. Conservative dosing is what I'm doing given the sides people report. The high dose goes in this weekend and hopefully I can report back. PT-141 is FDA approved (I believe) as an on demand mental aid for libido…. My last dose @ 1.25mg, with 1.75mg up next….Peppedia puts the max dose for women at 2mg daily.

You'll get an update from me 😂

Asking my doctor about HRT is something I caved on, and there's a blood test booked to check my hormones and whatnot. Creating my own HRT with grey and doctoring myself is probably within reach….but hormones feel like something I want a medical doctor monitoring for me.
 
Calm Logic said:

Even supposing it does work, the cardiovascular picture is worrying:


https://www.ahajournals.org/doi/10.1161/jaha.117.005790
Click to expand...
Interesting study! This one is new to me. Whether these findings translate to humans is something I do wonder about, though, since the atherosclerosis findings came from ApoE-deficient mice already very prone to developing it.

KP-10 has been given in human studies without apparent acute cardiovascular issues, but good long-term human data is something I don't think we have yet. So definitely an interesting finding, but whether this effect is ever replicated in humans is what I'd be curious to see.
 
Stace_wow said:

Thank you @Calm Logic. Kisspeptin is something I've been reading up on…with my family history, I'm very protective of my heart 😂

My experimenting has been with PT-141, so far unsuccessfully….there is apparently a threshold to hit there, and hit it I have not. Conservative dosing is what I'm doing given the sides people report. The high dose goes in this weekend and hopefully I can report back. PT-141 is FDA approved (I believe) as an on demand mental aid for libido…. My last dose @ 1.25mg, with 1.75mg up next….Peppedia puts the max dose for women at 2mg daily.

You'll get an update from me 😂

Asking my doctor about HRT is something I caved on, and there's a blood test booked to check my hormones and whatnot. Creating my own HRT with grey and doctoring myself is probably within reach….but hormones feel like something I want a medical doctor monitoring for me.
Click to expand...
Was the 141 increased?
 
Bep2030 said:

Hey! Kisspeptin-10 is on my list to try, to see whether it helps my libido, which has dropped quite a bit since being on reta.

If anyone here has used Kisspeptin-10 (especially females) for a similar reason, I'd love to hear about it. How did it go? Any difference in libido, and if so, how quickly?

On dosing I'm curious too: what was the dose, and how often each week? Any side effects, or anything else worth knowing?
Click to expand...
For a few days there was hope that it would work. No effect afterwards though. Actually your question was only about the female experience. But what people expect from it sits more at the level of feelings than of anything physical. Feel free to ignore my response, since a female I am not.
 
skaylife said:

Bep2030 said:

Hey! Kisspeptin-10 is on my list to try, to see whether it helps my libido, which has dropped quite a bit since being on reta.

If anyone here has used Kisspeptin-10 (especially females) for a similar reason, I'd love to hear about it. How did it go? Any difference in libido, and if so, how quickly?

On dosing I'm curious too: what was the dose, and how often each week? Any side effects, or anything else worth knowing?
Click to expand...
For a few days there was hope that it would work. No effect afterwards though. Actually your question was only about the female experience. But what people expect from it sits more at the level of feelings than of anything physical. Feel free to ignore my response, since a female I am not.
Click to expand...
A libido increasing peptide was something I was looking into as well, so at least one person got something from your answer, thanks 🙂 Nasal PT-141 is what I'm looking into buying, any experience with that?
 
ZetsuM said:

A libido increasing peptide was something I was looking into as well, so at least one person got something from your answer, thanks 🙂 Nasal PT-141 is what I'm looking into buying, any experience with that?
Click to expand...
I've given SQ PT-141 a shot and it's a good time. Just be warned, you might get surprise erections popping up 2-3 days afterward 😛
 
I've given pt141 a shot before, and honestly I'm a big fan. The downside is that it leaves me feeling sick, so my routine is to inject later in the day, snooze through the queasy part, and then get up with an erection.
 
Back
Top